IgG Isotype Mouse Monoclonal AKT1 Antibody CE / ISO / MSDS Certificated

Highly sensitive AKT1 Mouse Monoclonal Antibody

Cat.No. BT-MCA0023 Size: 20ul/50ul/100ul Datasheet Request

Product Information

Clonallity: Monoclonal

Applications: WB, IP, IHC, IF, ELISA

Source: mouse

Isotype: IgG

Protein Name: AKT1

Immunogen: AKT fusion protein

Synonyms: AKT, AKT (pan), AKT pan, AKT1, AKT1/2/3, pan AKT, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha, total AKT

Species specificity: human, mouse, rat

Calculated molecular weight: 56kDa

Recommended Dilution:

Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Store at 4°C for a month, for one year store at -20°C. When reconstituted in sterile pH 7.4 0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-20°C. Avoid repeated freeze/thaw cycles.

Background

The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with/without phospho- modification.​